By Osama M. Ouda, Mohamed Helmy
The advent of subsequent iteration Sequencing (NGS) applied sciences ended in a tremendous transformation within the approach scientists extract genetic info from organic platforms, revealing unlimited perception in regards to the genome, transcriptome and epigenome of any species. despite the fact that, with NGS, got here its personal demanding situations that require non-stop improvement within the sequencing applied sciences and bioinformatics research of the consequent uncooked information and meeting of the whole size genome and transcriptome. Such advancements result in impressive advancements of the functionality and insurance of sequencing and superior caliber for the assembled sequences, however, demanding situations corresponding to sequencing mistakes, dear processing and reminiscence utilization for meeting and sequencer particular error continues to be significant demanding situations within the field.
This publication goals to supply short overviews the NGS box with exact concentrate on the demanding situations dealing with the NGS box, together with details on varied experimental systems, meeting algorithms and software program instruments, meeting mistakes correction ways and the correlated challenges.
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